6th edition

Yes, there is a latest edition of Principles of Neural Science beyond the 2013 fifth edition. The sixth edition, published in 2021 by McGraw Hill Medical, is the current and most up-to-date version as of September 2025.823e6dce3379176f33

Key Details on the Sixth Edition:

Editors: Eric R. Kandel, John D. Koester, Sarah H. Mack (deceased), and Steven A. Siegelbaum

Publication Date: March 8, 2021

ISBN: 978-1259642234

Pages: Approximately 1,769

Publisher: McGraw Hill / McGraw Hill Medical

This edition builds on the foundational work of previous versions, incorporating significant advancements in neuroscience research since 2013. It features fully revised content across all chapters, over 300 new color illustrations, diagrams, radiology studies, and PET scans (totaling more than 2,200 images), and expanded discussions on emerging topics.

Major Updates and New Content:

New Chapters: Includes "The Computational Bases of Neural Circuits that Mediate Behavior," "Brain-Machine Interfaces," and "Decision-Making and Consciousness."

Expanded Coverage: Deeper exploration of human memory forms, neuroplasticity, genetics, and computational neuroscience.

Neurological Disorders: A new section on the neuroscientific principles underlying nervous system disorders, with detailed chapters on stroke, Parkinson's disease, multiple sclerosis, autism spectrum disorder, epilepsy, schizophrenia, and anxiety.

Structure: Organized into nine parts, covering everything from neural structure and function to perception, movement, learning, memory, language, cognition, and disorders. It emphasizes the integration of molecular, cellular, systems, and behavioral neuroscience.

The sixth edition remains the gold standard for neuroscience education and reference, used in advanced undergraduate, graduate, and medical programs. It reflects the rapid progress in the field, including insights from neuroimaging, electrophysiology, and brain-machine interfaces.

If you're looking to purchase or access it, it's available in hardcover, eBook, and online platforms like AccessNeurology. For specific chapters or comparisons to the fifth edition, let me know!